Insulin-1

Intermolecular

Cysteine 74 of H-2 class II histocompatibility antigen, A-D alpha chain and cysteine 107

A redox-regulated disulphide may form between cysteine 74 of H-2 class II histocompatibility antigen, A-D alpha chain and cysteine 107 of Insulin-1 (74 and 11 respectively in this structure).

Details

Redox score ?

PDB code

7qhp

Structure name

structure of i-ag7 with a bound hybrid insulin peptide

Structure deposition date

2021-12-13

Thiol separation (Å)

Half-sphere exposure sum ?

nan

Minimum pK_a ?

% buried

Peptide A name

H-2 class II histocompatibility antigen, A-D alpha chain

Peptide B name

Insulin-1

Peptide A accession

P04228

Peptide B accession

P01325

Peptide A residue number

Peptide B residue number

107

Ligandability

Cysteine 74 of H-2 class II histocompatibility antigen, A-D alpha chain

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 107 of Insulin-1